After last weekend’s humiliation on the south coast, Newcastle return to Premier League action tomorrow when they take on Manchester United. The Magpies have the chance to record their first league double over David Moyes’ side since 1931 but will have to do so without a number of first-team players.

The side that takes to the field tomorrow will be entirely different from the one that was victorious at Old Trafford earlier this season, as injuries begin to take their toll on Alan Pardew’s side.

Top scorer Loic Remy has returned to training but will not be fit for selection. Mathieu Debuchy is also missing with a groin problem and Tim Krul is still injured with the knock he picked up in the loss to Everton in Newcastle’s last home game. More bad news comes in the shape of Moussa Sissoko picking up a thigh injury in training and being ruled out for two to three weeks.

Is it a coincidence that Newcastle’s season is already cemented in mid-table mediocrity and almost all of their realistic World Cup players are injured?

Davide Santon will likely return to the starting line-up for the Magpies at either right or left back, with Massadio Haidara, Paul Dummett or Mapou Yanga-Mbiwa on the other flank.

There could be more youth potential involved in the squad, with Adam Armstrong fresh from scoring for England under 17’s recently and Rolando Aarons signing a professional contract earlier this week. Remie Streete also has hopes of making the squad.

Gabriel Obertan will not be in the squad against his former club though, as he remains drastically out of favour and is likely already looking for a new club as he prepares to be turfed out in the summer.

Man United come to Tyneside four days after holding Bayern Munich in the Champions League quarter final and with the second leg next week, could opt to rest some of their top players. Wayne Rooney would be the most likely to get a weekend off, a welcome sight for Newcastle fans who are sick of seeing the 28-year-old score against their side so regularly.

Robin van Persie is injured and won’t play, while Rafael and Alexander Buttner are doubts. Juan Mata will definitely play as he is ineligible for the Champions League.

David Moyes’ side still have hopes of finishing in the top six and could overtake Tottenham with another away win while Newcastle can again move above Southampton if they manage to turn over the 20-time Premier League champions.